There is a well knoww issue that Chrome is not blocking video ads inside videos, even if the adblock rules state the video ad should be blocked. And I am not talking about YouTube videos, either.

I have found a workaround for those intrusive autoplay non-skipable videos that some sites use. It requires some work, but it pays of in the end. The solutions is create a new rule in the Adblock are, with the domain the video ad is streaming from.

Something like this:

$domain=adserver.domain.de

The solution is not working 100%, but for some sites it does.